It is as different from the anime most watch as possible it begins with a chance meeting of these 2 samurai who want to kill each other and this 15 year old girl looking for a samurai that smells like sunflowers. Really that is the plot.
My description is backed up by Wikipedia which goes in to more detail
A young woman named Fuu is working as a waitress in a tea shop when she is abused by a band of samurai. She is saved by a mysterious rogue named Mugen and a young rōnin named Jin. Mugen attacks Jin after he proves to be a worthy opponent. The pair begin fighting one another and inadvertently cause the death of Shibui Tomonoshina, the magistrate’s son. For this crime, they are to be executed. With help from Fuu, they are able to escape execution. In return, Fuu asks them to travel with her to find “the samurai who smells of sunflowers”.
It’s really a fun series to watch as every episode is so different you really can’t even guess of what trouble these 3 characters will get into or who they meet. Everything from Elvis type characters, to an artist, and even terrorists. They get out of the last one by burning the terrorist supply of weed. Really I am not joking, they do that and more. Yes, everyone does get stoned.
Fun series, great action, a good mix of both and more. I could go on and on on why this is such a great series.
Here is a video of short clips
If you like what you see the DVDs are fairly cheap I picked up my copy for $23 and the series is available for viewing on crunchyroll